Ending the Acacian Schism
Epiphanius inherited the settlement his predecessor had reached with Pope Hormisdas to heal the Acacian Schism, the long rupture in communion between Constantinople and Rome over the reception of the Council of Chalcedon. On his accession he wrote to Hormisdas announcing his acceptance of the agreed conditions of reconciliation and his adherence to the creed and decrees of Chalcedon.
He affirmed the doctrinal standards of the councils of Nicaea, Ephesus, Constantinople, and Chalcedon, together with the writings of Pope Leo I, and received bishops who renounced their errors and returned to Orthodox communion. As a token of restored unity he sent gifts to Rome, reported to include a jewelled gold chalice, a gold paten, a silver chalice, and silk veils. A council he convened at Constantinople condemned Severus of Antioch.